Volumen: 19 # Number : 3
Publication Date : Septiembre - Diciembre Year: 2015
Use of immunoglobulin in patient with
primary immune thrombocytopenia. Case report
Authors: Videa-Irias EO, Bonilla-Lanza NA, Aguilar-Gudiel KJ.
Abstract: Primary immune thrombocytopenia is an autoimmune
disease characterized by hemorrhagic premature
destruction of platelets due to the binding of an
autoantibody, usually of the IgG class. We present
the case of a 25 years old male college student from
eastern Honduras, assited at the Emergency Unit of
a private hospital in Tegucigalpa, for generalized
petechiae and ecchymosis of 4 days of evolution.
He didn’t refer neither personal nor familial pathologic
antecedents and denied recent history of acute
infectious diseases. Hemogram made at admission
reported (2,000/L), FSP, ANA, antiphospholipid antibodies,
serology HIV, HBV, HCV negative. Helicobacter
pylori positive in stool. Primary immune
thrombocytopenia was diagnosed. The patient was
managed with methylprednisolone 1g each day for
three days and platelets transfusions, with a partial
response, so it was decided to start on the 6th
day of the disease treatment with immunoglobulins,
with doses of 75g IV for two days. The patient progressed
satisfactorily, and clinical improvement and
hematologic remission are achieved.
Key words: Immunoglobulin,
primary immune thrombocytopenia.
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