Volumen: 17 # Number : 2
Publication Date : Mayo - Agosto Year: 2013
Authors: del Val LA, González Achával MG, Ghione S,
Gómez S, Molina A, Polka L, Hadad M, Correa M, Hill L, Sala JP
Abstract: We analyzed 349 patients from a total of 428 diagnosed with venous thromboembolism (VTE) recorded over a period of 15 years between 1996 and 2011, all on oral anticoagulant therapy (OAT) with warfarin. Objectives: To estimate the population characteristics, diagnosis, etiology, time tracking, attendance at consultation and cumulative rate of recurrent VTE, composite endpoint of VTE and death, and bleeding. Methods and Material: We studied 428 patients with a diagnosis
of deep vein thrombosis (DVT) and / or acute pulmonary
thromboembolism (APTE) with OAT registered in an electronic system SintroMc. 79 patients who had not achieved a time tracking of 3 months were excluded from the study. Statistical
analysis were performed with InfoStat (National University
of Cordoba) Results: 52 % presented DVT diagnosis; 32% APTE; DVT and APTE 15%. Mean age 61.52 years (13-90). 54% male. Follow-up time of 0.25 to 15 years with a total of 661.08 patient-years. Idiopathic etiology 49%, 19% malignancy,
thrombophilia 11%, 9% surgery, 11% miscellaneous. 26% completed treatment, 12% left the study, 29% are still under
treatment, 6% died, 21% got lost during follow up and 5% switched to another institution. Cumulative recurrence rate for VTE was 4.58% at 15 years, 9.74% had combined events and 10.60% hemorrhage. Conclusions: Population characteristics
are similar to those in the literature. The total follow-up time was prolonged. There was a high rate of abandonment of treatment and patients with uncertain follow up. Recurrence rates for VTE and bleeding and combined endpoint were lower
than those reported in the literature.
Key words: venous thromboembolism, recurrent venous thromboembolism,
oral anticoagulant therapy
Pages : 127-132
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