Volumen: 16 # Number : 3
Publication Date : Septiembre - Diciembre Year: 2012
Authors: Solessi M.S.1, 4, Bonadeo J.1, Tamashiro M.1, Aliano R.1,
Sorrentino M.1, De Zan M.2, Barcala V.3, García Rivello H.3,
Bezares R.F.4, Iastrebner M.1
Abstract: We report a 54-year-old female consulting for vertiginous
syndrome, radial paralysis, a previous diagnosis
of systemic lupus erythematosus (SLE), and widespread
chronic ulcerative lesions (pathologic diagnosis: lobar
panniculitis with vasculitis). A monoclonal hypergammaglobulinemia
(IgG lambda), was detected, as well
as positive cryoglobulins and bone marrow infiltration
by cells with a “foamy” appearance corresponding to a
small population of plasmocytes with pathological
phenotype as showed by flow cytometry. Pathologic and
immunohistochemistry studies confirmed the finding
of plasma cells with atypical morphology. The diagnosis
was multiple myeloma with cryoglobulinemic
vasculitis.
Key words: multiple myeloma, foamy plasma cell,
cryoglogulinemic vasculitis
Pages : 216-218
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