Volumen: 19 # Number : 2
Publication Date : Mayo - Agosto Year: 2015
Acute Myeloid Leukemia with trisomy four
Authors: Máspero G, Garcia M V, Ricchi B N,
Cabral A C, Nibeyro G, Basquiera A L.
Abstract: Cytogenetic abnormalities are detected in nearly
50% of adult patients with acute myeloid leukemia
at diagnosis. This finding is important for prognosis
and classification.
Trisomy 4 is a rare cytogenetic abnormality, present
in only 1 % of abnormal karyotypes.
We report a 39 years old woman with a diagnosis of
acute myeloid leukemia, a chromosome 4 trisomy
and blasts of peculiar appearance -with intracytoplasmic
vacuoles- in blood and bone marrow.
Key words: acute myeloid leukemia,
chromosome 4 trisomy,
chromosome abnormalities
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