Volumen: 18 # Number : 1
Publication Date : Enero - Abril Year: 2014
Langerhans´cell histiocytosis
Authors: Casanovas A, Elena G, Rosso D
Abstract: Langerhans’ cell histiocytosis (LCH), previously known as histiocytosis X, is a rare disease. It is characterized by the accumulation and proliferation of histiocytes, eosinophils and Langerhans’ cells with Birbeck granules detected by electron microscopy. It involves single organs or systems or can present as a multisystem disease. The diagnosis is made by biopsy of the lesion and confirming the presence of CD1a and / or CD207 on it. The clinical presentation may vary widely, ranging from benign self-limiting types with spontaneous regression to slowly progressive malignant
disease.
Key words: Langerhans’ cell histiocytosis
Diagnosis, Treatment
Pages : 60-66
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